Laminated Membrane Surface and Osmiophilic Inclusions in Avian Lung Epithelium

A study of the fine structure of the avian lung revealed the presence of a unique laminated membrane surface and associated osmiophilic inclusions in epithelial cells of the tertiary bronchi and atria. These structures were not found in the air-capillary epithelium. Each lamination of the membrane surface had the appearance and dimensions of the unit membrane. It is suggested that the laminated membrane surface is associated with the formation of the osmiophilic inclusions and that these inclusions compare with those described in mammalian alveolar epithelium. It is further suggested that the laminated membrane surface is lipoprotein or phospholipid in composition and is responsible for the surface-tension-reducing properties of avian lung extracts.